B\u1ed9 x\u00e9t nghi\u1ec7m FERRITIN ELISA \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ch\u1ec9 s\u1eed d\u1ee5ng cho ph\u00f2ng th\u00ed nghi\u1ec7m.<\/p>\n
Ph\u01b0\u01a1ng ph\u00e1p so m\u00e0u enzyme mi\u1ec5n d\u1ecbch d\u00f9ng \u0111\u1ec3 \u0111\u1ecbnh l\u01b0\u1ee3ng n\u1ed3ng \u0111\u1ed9 Ferritin trong huy\u1ebft thanh ho\u1eb7c huy\u1ebft t\u01b0\u01a1ng ng\u01b0\u1eddi.<\/p>\n
Ferritin l\u00e0 m\u1ed9t protein h\u00ecnh c\u1ea7u \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y ch\u1ee7 y\u1ebfu \u1edf gan v\u00e0 c\u00f3 th\u1ec3 t\u00edch tr\u1eef kho\u1ea3ng 2.250 ion s\u1eaft (Fe3+). C\u00e1c ph\u00e2n t\u1eed ferritin bao g\u1ed3m m\u1ed9t v\u1ecf protein (apoferritin) ch\u1ee9a c\u00e1c ti\u1ec3u \u0111\u01a1n v\u1ecb n\u1eb7ng v\u00e0 nh\u1eb9, bao quanh m\u1ed9t l\u00f5i tinh th\u1ec3 c\u00f3 ch\u1ee9a oxit s\u1eaft v\u00e0 ph\u1ed1t ph\u00e1t.<\/p>\n
Ferritin \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p \u1edf gan, l\u00e1 l\u00e1ch v\u00e0 nhi\u1ec1u m\u00f4 kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3, v\u1edbi n\u1ed3ng \u0111\u1ed9 l\u1edbn \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong gan, l\u00e1 l\u00e1ch, t\u1ee7y x\u01b0\u01a1ng, v\u00e0 ni\u00eam m\u1ea1c ru\u1ed9t.<\/p>\n
N\u1ed3ng \u0111\u1ed9 ferritin \u0111o \u0111\u01b0\u1ee3c c\u00f3 m\u1ed9t m\u1ed1i t\u01b0\u01a1ng quan tr\u1ef1c ti\u1ebfp v\u1edbi t\u1ed5ng l\u01b0\u1ee3ng s\u1eaft \u0111\u01b0\u1ee3c t\u00edch tr\u1eef trong c\u01a1 th\u1ec3. N\u1ebfu ferritin cao t\u1ee9c l\u00e0 s\u1eaft d\u01b0 th\u1eeba, v\u00e0 s\u1ebd \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua ph\u00e2n. N\u1ebfu ferritin th\u1ea5p c\u00f3 nguy c\u01a1 thi\u1ebfu s\u1eaft, m\u00e0 s\u1edbm hay mu\u1ed9n c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u.<\/p>\n
Trong c\u00e1c x\u00e9t nghi\u1ec7m c\u1ee7a b\u1ec7nh thi\u1ebfu m\u00e1u, ferritin huy\u1ebft thanh l\u00e0 x\u00e9t nghi\u1ec7m nh\u1ea1y nh\u1ea5t \u0111\u1ed1i v\u1edbi b\u1ec7nh thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft. Ng\u01b0\u1ee3c l\u1ea1i, n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh b\u00ecnh th\u01b0\u1eddng ho\u1eb7c t\u0103ng l\u00ean trong thi\u1ebfu m\u00e1u li\u00ean quan \u0111\u1ebfn b\u1ec7nh m\u1ea1n t\u00ednh. N\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh t\u0103ng cao \u0111\u00e3 \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y \u1edf b\u1ec7nh gan c\u1ea5p t\u00ednh v\u00e0 m\u1ea1n t\u00ednh, b\u1ec7nh u h\u1ea1ch b\u1ea1ch huy\u1ebft \u00e1c t\u00ednh (b\u1ec7nh b\u1ea1ch c\u1ea7u c\u1ea5p v\u00e0 u lympho Hodgkin). N\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh cao c\u0169ng li\u00ean quan \u0111\u1ebfn nguy c\u01a1 b\u1ecb nh\u1ed3i m\u00e1u c\u01a1 tim \u1edf nam gi\u1edbi t\u0103ng cao. Ferritin c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t d\u1ea5u hi\u1ec7u c\u1ee7a r\u1ed1i lo\u1ea1n qu\u00e1 t\u1ea3i s\u1eaft, ch\u1eb3ng h\u1ea1n nh\u01b0 haemochromatosis (b\u1ec7nh qu\u00e1 t\u1ea3i s\u1eaft) trong \u0111\u00f3 n\u1ed3ng \u0111\u1ed9 ferritin c\u00f3 th\u1ec3 t\u0103ng l\u00ean b\u1ea5t th\u01b0\u1eddng.<\/p>\n
Ferritin l\u00e0 m\u1ed9t ch\u1ea5t ph\u1ea3n \u1ee9ng giai \u0111o\u1ea1n c\u1ea5p t\u00ednh, n\u00f3 th\u01b0\u1eddng t\u0103ng l\u00ean trong qu\u00e1 tr\u00ecnh c\u1ee7a b\u1ec7nh.<\/p>\n
S\u1eaft t\u1ef1 do g\u00e2y \u0111\u1ed9c cho t\u1ebf b\u00e0o, v\u00e0 c\u01a1 th\u1ec3 c\u00f3 m\u1ed9t c\u01a1 ch\u1ebf b\u1ea3o v\u1ec7 tinh vi \u0111\u1ec3 g\u1eafn k\u1ebft s\u1eaft trong c\u00e1c khoang m\u00f4 kh\u00e1c nhau. B\u00ean trong t\u1ebf b\u00e0o, s\u1eaft \u0111\u01b0\u1ee3c t\u00edch tr\u1eef \u1edf d\u1ea1ng ph\u1ee9c h\u1ee3p v\u1edbi protein nh\u01b0 m\u1ed9t ferritin hay hemosiderin. Apoferritin g\u1eafn v\u1edbi Fe2+ t\u1ef1 do v\u00e0 t\u00edch tr\u1eef \u1edf tr\u1ea1ng th\u00e1i Fe3+. Trong \u0111i\u1ec1u ki\u1ec7n \u1ed5n \u0111\u1ecbnh, n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh t\u01b0\u01a1ng quan v\u1edbi t\u1ed5ng l\u01b0\u1ee3ng s\u1eaft t\u00edch tr\u1eef trong c\u01a1 th\u1ec3; do \u0111\u00f3, n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh l\u00e0 x\u00e9t nghi\u1ec7m thu\u1eadn ti\u1ec7n nh\u1ea5t trong ph\u00f2ng th\u00ed nghi\u1ec7m \u0111\u1ec3 \u01b0\u1edbc l\u01b0\u1ee3ng s\u1eaft d\u1ef1 tr\u1eef.<\/p>","protected":false},"excerpt":{"rendered":"
H\u00e3ng DRG Instruments – \u0110\u1ee9c<\/p>\n